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Modifications in the Mountains
BY RALPh A. BRADShAW AND KAtI F. MEDZIhRADSZKY
Against the majestic backdrop of the Sierra Nevadas illustrations of extensive applications of mass spectrom-and the deep blue of Lake Tahoe, the ASBMB hosted
etry to the determination of PTMs. This was followed by
some 70 scientists at the Granlibakken Resort for three
sessions on glycosylation (featuring invited talks by Jim
days of presentations and discussions on the nuances of
Paulson, Scripps Institute, La Jolla, and Jerry Hart, Johns
the post-translational modifications (PTMs) of proteins.
Hopkins, Baltimore), phosphorylation (Pierre Thibault,
The focus of the meeting was two-fold: 1) technologi-
Universite de Montreal), and oxidation (Cathy Costello,
cal advances in the determination of both old and new
Boston University, and Judy Klinman, University of Cali-
alterations, and 2) the evaluation of related physiological
fornia, Berkeley) interspersed with sessions devoted to
responses.
unusual modifications (Kati Medzihradszky, UCSF, and
The meeting, organized by Kati Medzihradszky and
